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"The Fix"
After losing a bet with Wilson over a boxing match, House is convinced that the fighter he bet on (Kevin Phillips) has an underlying medical condition that cost him the fight. While he tries to prove it, he leaves his team alone to help a bomb scientist (Linda Park) who suffered a seizure. Meanwhile, House may be experimenting with a new drug to help his leg pain.
Final Diagnosis: Dr. Lee: Spanish fly (cantherides) poisoning; Terry: Glomus tumor
"Then I Really Got Scared"
Bree finds out Chuck Vance has researched her; they later do something surprising, involving a hooker; Juanita is unable to sleep after watching a horror movie; Paul checks his food for any sign of antifreeze; Susan brings refreshments that could be fatal to people; Tom and Lynette have a vacation argument.
"Changes"
The team takes on the case of a lottery winner (Donal Logue) suffering from paralysis and multiple types of cancer, and they must figure out if it his new millionaire lifestyle that is making him sick. Meanwhile, Cuddy's mother threatens to sue the hospital over her treatment, and Foreman and Chase make a bet over who is repressing the uglier side of their personality more.
"I'll Swallow Poison on Sunday"
After taking illegal action, Bree is caught by Chuck Vance, a police officer; someone, possibly Felicia, has been poisoning Paul with antifreeze; despite a family obligation, Tom must complete his work.
"The Lies Ill-Concealed"
When Tom attends a business seminar, Lynette attends to flower arrangements; she later tries to pose as a successful woman to no avail; Susan has nightmares about Paul Young; Gabrielle is forbidden to be friends with Bree by Carlos; Felicia tries to get help from Mrs. McCluskey in an attempt to get revenge against Paul.
"Last Temptation"
Thirteen returns as Masters prepares to graduate. Her final case is that of a teenage girl (Michelle DeFraites) preparing to become the youngest sailer to circumnavigate the globe. As the case progresses, House offers Masters an internship in return for forging her lab work requirements. Initially refusing to compromise her integrity, her patient takes a turn for the worse, and she has to make a decision: her principles, or her patient's life?
Final Diagnosis: Lymphangiosarcoma
"Moments in the Woods"
Susan makes a huge bet at a casino; Renee teaches Lynette to order a saleslady around; Carlos finds out that Andrew was responsible for his mother's hit and run; Felicia tries to make peace with Paul, despite her hatred of him.
"The Dig"
House discovers that Thirteen has been in prison for the past six months, and attempts to discover what crime she was guilty of, while also enlisting her help in defeating his spud gun nemesis. Meanwhile, the team takes the case of a teacher (Terry Maratos) who is coughing up blood. When they search his home, they find it filled with garbage. But even more disturbing is finding his wife (Kimberlee Peterson) hiding beneath the filth.
Final Diagnosis: Nina: Ehlers-Danlos syndrome.
"Everything's Different, Nothing's Changed"
Paul tries to stand between Susan and her kidney transplant; Felicia is released from prison and swears revenge against Paul; Gabrielle is furious about a neighborhood party planned by Renee; Tom is caught between working with Carlos and a job opportunity; Andrew's drinking concerns Bree.
