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"The Fix"
After losing a bet with Wilson over a boxing match, House is convinced that the fighter he bet on (Kevin Phillips) has an underlying medical condition that cost him the fight. While he tries to prove it, he leaves his team alone to help a bomb scientist (Linda Park) who suffered a seizure. Meanwhile, House may be experimenting with a new drug to help his leg pain.
Final Diagnosis: Dr. Lee: Spanish fly (cantherides) poisoning; Terry: Glomus tumor
"Changes"
The team takes on the case of a lottery winner (Donal Logue) suffering from paralysis and multiple types of cancer, and they must figure out if it his new millionaire lifestyle that is making him sick. Meanwhile, Cuddy's mother threatens to sue the hospital over her treatment, and Foreman and Chase make a bet over who is repressing the uglier side of their personality more.
"Last Temptation"
Thirteen returns as Masters prepares to graduate. Her final case is that of a teenage girl (Michelle DeFraites) preparing to become the youngest sailer to circumnavigate the globe. As the case progresses, House offers Masters an internship in return for forging her lab work requirements. Initially refusing to compromise her integrity, her patient takes a turn for the worse, and she has to make a decision: her principles, or her patient's life?
Final Diagnosis: Lymphangiosarcoma
"The Dig"
House discovers that Thirteen has been in prison for the past six months, and attempts to discover what crime she was guilty of, while also enlisting her help in defeating his spud gun nemesis. Meanwhile, the team takes the case of a teacher (Terry Maratos) who is coughing up blood. When they search his home, they find it filled with garbage. But even more disturbing is finding his wife (Kimberlee Peterson) hiding beneath the filth.
Final Diagnosis: Nina: Ehlers-Danlos syndrome.
