Hardwicke, who also recently made Red Riding Hood, doesn't have any personal experience of puckering up to Pattinson's lips but still lavished praise on his skills.
Both Pattinson and his co-star Taylor Lautner are up for Best Kiss at the MTV Movie Awards for their on-screen smooches with Kristen Stewart.
Hardwicke refused to pick a favourite to win telling MTV News: 'Maybe it can be a tie? That would be perfect! I think [that's] the safest solution to this problem.'
She added that she was still thrilled that fans were so devoted to the vampire franchise.
'I love it that people are so passionate about it and...are really into it... Rob and Kristen and everybody's been able to just keep it going and keep people loving it all this time... I think it's awesome. It's great.'
Meanwhile, Pattinson has been snapped pulling a silly face on the set of his new movie, Cosmopolis.
The Twilight Saga hunk will play financial whizz kid Eric Packer who bets his entire fortune against the rise of the yen in the big screen adaptation of Don DeLillo's novel of the same name.